| ID | DRAMP00001 |
|---|---|
| Sequence | GSGVIPTISHECHMNSFQFVFTCCS |
| Length | 25 |
| Name | Variacin (Bacteriocin) |
| Source | Micrococcus varians (Gram-positive bacteria) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Lactobacillus helveticus (+++), L. bulgaricus (+++), Lactobacillus lactis (++), Lactobacillus delbrueckii (+++), Lactobacillus acidophilus (++), Lactobacillus plantarum (+), Lactobacillus sake (LSK) (++), Lactobacillus curvatus (++), Leuconostoc mesenteroides (+), Streptococcus thermophilus (++), Lactococcus lactis (SL2) (++), Enterococcus faecalis (++), Enterococcus faecium (++), Listeria innocua (++), Listeria monocytogenes (++++), Listeria welhia (++).##Note: Inhibitory activity tested with supernatant adjusted to pH 7. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not found |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8633879 |
Physicochemical Properties
| Residues | 25 |
|---|---|
| Sequence | GSGVIPTISHECHMNSFQFVFTCCS |
| Molecular Weight | 2732.098 |
| Grand Average of Hydropathy | 0.452 |
| Isoelectric Point | 5.98 |
| Charge at pH 7.4 | -1.442 |
| Secondary Structure | Helix: 0.280, Turn: 0.320, Sheet: 0.080 |
| Instability Index | 36.048 |
| Aromaticity | 0.12 |