Basic Information

IDDRAMP00005
SequenceSLGPAIKATRQVCPKATRFVTVSCKKSDCQ
Length30
NameEpicidin 280 (Bacteriocin)
SourceStaphylococcus epidermidis BN 280 (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Staphylococcus simulans 22 (MIC=0.304 μg/ml), Staphylococcus epidermidis 5 (MIC=3.85 μg/ml), Micrococcus luteus ATCC4698 (MIC=9.7 μg/ml), Staphylococcus carnosus TM300 (MIC=0.175 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationOxypropionylation
C-terminal ModificationNot metioned clearly
Linear/Cyclic/BranchedCyclic (very possibly)
Uniprot O54220
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9726851

Physicochemical Properties

Residues30
SequenceSLGPAIKATRQVCPKATRFVTVSCKKSDCQ
Molecular Weight3223.791
Grand Average of Hydropathy-0.22
Isoelectric Point9.751
Charge at pH 7.44.17
Secondary StructureHelix: 0.200, Turn: 0.200, Sheet: 0.133
Instability Index29.107
Aromaticity0.033

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