Basic Information
| ID | DRAMP00012 |
|---|
| Sequence | TITLSTCAILSKPLGNNGYLCTVTKECMPSCN |
|---|
| Length | 32 |
|---|
| Name | Lantibiotic lichenicidin VK21 A1 (LchA1; Lchalpha; Bacteriocin) |
|---|
| Source | Bacillus licheniformis (strain ATCC 14580/VK21/DSM 13) (Gram-positive bacteria) |
|---|
| Activity | Antimicrobial, Antibacterial |
|---|
| Pathogen | Only Lchalpha: Bacillus megaterium VKM41 (IC50=1.8 uM), Bacillus subtilis L1 (IC50=9 uM), Rhodococcus sp. SS2 (IC50=9 uM), Micrococcus luteus B1314 (IC50=1.2 uM), Staphylococcus aureus 209p (IC50=3.1 uM).##Lchalpha+Lchbeta: Bacillus megaterium VKM41 (IC50=0.12 uM), Bacillus subtilis L1 (IC50=0.64 uM), Rhodococcus sp. SS2 (IC50=0.64 uM), Micrococcus luteus B1314 (IC50=0.09 uM), Staphylococcus aureus 209p (IC50=0.64 uM). |
|---|
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
|---|
| Cytotoxicity | Not included yet |
|---|
| N-terminal Modification | Not included yet |
|---|
| C-terminal Modification | Not included yet |
|---|
| Linear/Cyclic/Branched | Not included yet |
|---|
| Uniprot |
P86475, E0YCK1, Q65DC4, Q62NU5 |
|---|
| PDB |
2KTN |
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 19561184, 19707558, 20578714 |
|---|
