Basic Information

IDDRAMP00015
SequenceSTIVCVSLRICNWSLRFCPSFKVRCPM
Length27
NameGeobacillin II (nisin analog; Bacteriocin)
SourceGeobacillus thermodenitrificans NG80-2 (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus Z4222, Bacillus subtilis ATCC 6633.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization between S29 and C33
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22431611

Physicochemical Properties

Residues27
SequenceSTIVCVSLRICNWSLRFCPSFKVRCPM
Molecular Weight3146.839
Grand Average of Hydropathy0.659
Isoelectric Point9.371
Charge at pH 7.43.153
Secondary StructureHelix: 0.370, Turn: 0.259, Sheet: 0.111
Instability Index24.015
Aromaticity0.111

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