Basic Information

IDDRAMP00191
SequenceGGAGHVPEYFVGIGTPISFYG
Length21
NameMicrocin J25 (MccJ25; Bacteriocin)
SourceEscherichia coli AY25 (Gram-negative bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli BM21 (MIC=0.08 µg/ml), E. coli AB1133 (MIC=0.02 µg/ml), E. coli RYC816 (MIC=0.04 µg/ml), E. coli AY29 (MIC=0.04 µg/ml), Salmonella species, Shigella flexneri.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationCyclization of a N-terminal between Gly and Glu
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot Q9X2V7
PDB 1Q71, 1PP5
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1429464, 10092860, 14531690, 14531661

Physicochemical Properties

Residues21
SequenceGGAGHVPEYFVGIGTPISFYG
Molecular Weight2125.337
Grand Average of Hydropathy0.4
Isoelectric Point5.24
Charge at pH 7.4-1.41
Secondary StructureHelix: 0.381, Turn: 0.429, Sheet: 0.095
Instability Index28.158
Aromaticity0.19

Similar Structure Search

Candidates based on structure

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