| ID | DRAMP00201 |
|---|---|
| Sequence | SCNCVCGVCCSCSP |
| Length | 14 |
| Name | Amythiamicin A/B (Bacteriocin) |
| Source | Amycolatopsis sp. (strain MI481-42F4 / FERM P-12739) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Staphylococcus aureus MS9610 (MIC=0.2 µg/ml), Methicillin-resistant S. aureus (MIC=0.2 µg/ml), Staphylococcus aureus FDA209P (MIC=0.1 µg/ml), Micrococcus luteus FDA16 (MIC=0.1 µg/ml), M. luteus IFO3333 (MIC=0.78 µg/ml), M. luteus PCI1001 (MIC=0.2 µg/ml), Bacillus anthracis (MIC=0.1 µg/ml), B. subtilis NRRL B-558 (MIC=0.2 µg/ml), B. subtilis PCI219 (MIC=0.2 µg/ml), B. cereus ATCC 10702 (MIC=0.1 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P0C912 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 8040071 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | SCNCVCGVCCSCSP |
| Molecular Weight | 1364.636 |
| Grand Average of Hydropathy | 1.107 |
| Isoelectric Point | 5.229 |
| Charge at pH 7.4 | -0.894 |
| Secondary Structure | Helix: 0.143, Turn: 0.429, Sheet: 0.000 |
| Instability Index | 79.8 |
| Aromaticity | 0 |