| ID | DRAMP00204 |
|---|---|
| Sequence | STNCFCYICCSCSS |
| Length | 14 |
| Name | Thiocillin GE37468 (Antibiotic GE37468; Bacteriocin) |
| Source | Streptomyces sp. (Gram-positive bacteria) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | Gram-positive bacteria: Bacillus subtilis (MIC=0.047 µg/ml), Staphylococcus aureus (MRSA) (MIC=0.047 µg/ml). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | No cytotoxicity information found |
| N-terminal Modification | Cyclization |
| C-terminal Modification | Free |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot | P0C8P9, G1ECL0 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 21788474 |
Physicochemical Properties
| Residues | 14 |
|---|---|
| Sequence | STNCFCYICCSCSS |
| Molecular Weight | 1520.75 |
| Grand Average of Hydropathy | 0.793 |
| Isoelectric Point | 5.23 |
| Charge at pH 7.4 | -0.872 |
| Secondary Structure | Helix: 0.214, Turn: 0.357, Sheet: 0.000 |
| Instability Index | 33.536 |
| Aromaticity | 0.143 |