Basic Information
| ID | DRAMP00765 |
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| Sequence | RPRCWIKIKFRCKSLKF |
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| Length | 17 |
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| Name | Piceain 2 (Plants) |
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| Source | Picea sitchensis |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=9.38 µg/ml), S. aureus ATCC 43300 (MIC=18.75 µg/ml);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=37.5 µg/ml), Escherichia coli ML-35P (MIC=37.5 µg/ml), Escherichia coli 08040722 (CI) (MIC=75 µg/ml), Escherichia coli 08A866 (CI) (MIC=37.5 µg/ml), Pseudomonas aeruginosa PA01 (MIC=9.38 µg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=18.75 µg/ml), Pseudomonas aeruginosa 08031014 (CI) (MIC=37.5 µg/ml).##Yeast: Candida albicans ATCC 20032 (MIC=18.75 µg/ml). |
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| Hemolytic Activity | [Ref.21644248] At the concentration of 0.0625 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.6% & 2.2%; At the concentration of 0.125 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 0.8% & 4.7%; At the concentration of 0.25 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.2%&5.2%; At the concentration of 0.5 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 5.3% & 12.4%; At the concentration of 1 mg/ml, Piceain 1 induced human & rabbit red cell hemolysis of 11.3% & 66.3%. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 21644248 |
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