Basic Information

IDDRAMP00933
SequenceSAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC
Length76
NameAntimicrobial peptide 1 (AMP1; MiAMP1; Plant defensin)
SourceMacadamia integrifolia (Macadamia nut)
ActivityAntimicrobial, Antibacterial, Antifungal
PathogenAlternaria helianthi (MIC=2-5 µg/ml), Botrytis cinerea (MIC=5-10 µg/ml), Ceratocystis parodoxa (MIC=20 µg/ml), Colletotrichum gloeosporioides (MIC=2-5 µg/ml), Fusurium oxysporum (MIC=2-5 µg/ml), Leptosphaeria maculans (MIC=5 µg/ml), Macrophomina phaseolina (MIC<25 µg/ml), Phytophthoru cryptogea (MIC=5-10 µg/ml), Pythium graminicola (MIC=5 µg/ml), Sclerotinia sclerotiorum spores (MIC=5 µg/ml), Sclerotinia sclerotiorum mycelia (MIC=50 µg/ml), Verticilium dahliae (MIC=2 µg/ml), Clavibacter michiganensis (MIC<10 µg/ml), Saccharomyces cerevisiae (MIC=2-5 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization of a C-terminal Cys residue (forming a disulfide bond)
Linear/Cyclic/BranchedCyclic
Uniprot P80915
PDB 1C01
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9108242, 10543955

Physicochemical Properties

Residues76
SequenceSAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC
Molecular Weight8137.969
Grand Average of Hydropathy-0.321
Isoelectric Point9.075
Charge at pH 7.44.163
Secondary StructureHelix: 0.224, Turn: 0.329, Sheet: 0.145
Instability Index17.78
Aromaticity0.145

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.