Basic Information

IDDRAMP00958
SequenceKSCCRSTTARNIYNGCRVPGTARPVCAKKSGCKIQEAKKCEPPYD
Length45
NamePp-AMP2 (P. pubescens AMP2; Plant defensin)
SourcePhyllostachys pubescens (Japanese bamboo shoots)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Erwinia carotovora (IC50=20 µg/ml), Agrobacterium radiobacter (IC50=13 µg/ml), Agrobacterium rhizogenes (IC50=15 µg/ml);##Gram-positive bacteria: Clavibacter michiganensis (IC50=18 µg/ml), Curtobacterium flaccumfaciens (IC50=20 µg/ml).##Fungi: Fusarium oxysporum (IC50=2 µg/ml), Geotrichum candidum (IC50=2 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15784998

Physicochemical Properties

Residues45
SequenceKSCCRSTTARNIYNGCRVPGTARPVCAKKSGCKIQEAKKCEPPYD
Molecular Weight4919.693
Grand Average of Hydropathy-0.833
Isoelectric Point9.418
Charge at pH 7.46.394
Secondary StructureHelix: 0.133, Turn: 0.267, Sheet: 0.133
Instability Index63.122
Aromaticity0.044

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Candidates based on structure

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