Basic Information

IDDRAMP01046
SequenceGYGGHGGHGGHGGHGGHGGHGHGGGGHG
Length28
NameShepherin I (fragement of shep-GRP; Plants)
SourceCapsella bursa-pastoris (shepherd's purse)
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Erwinia herbicola (IC50=62 µg/ml), Escherichia coli (IC50<2.5 µg/ml), Pseudomonas putida (IC50<2.5 µg/ml), Pseudomonas syringae (IC50<2.5 µg/ml), Salmonella typhimurium (IC50<2.5 µg/ml), Serratia sp. (IC50=8 µg/ml).##Fungi: Candida albicans (IC50=8 µg/ml), Cryptococcus neoformans (IC50<2.5 µg/ml), Saccharomyces cerevisiae (IC50<7 µg/ml), Alternaria alternata (IC50<7 µg/ml), Aspergillus flavus (IC50=65 µg/ml), Fusarium culmorum (IC50=72 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11117262

Physicochemical Properties

Residues28
SequenceGYGGHGGHGGHGGHGGHGGHGHGGGGHG
Molecular Weight2362.278
Grand Average of Hydropathy-1.232
Isoelectric Point7.283
Charge at pH 7.4-0.152
Secondary StructureHelix: 0.036, Turn: 0.679, Sheet: 0.000
Instability Index13.614
Aromaticity0.036

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Candidates based on structure

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