Basic Information

IDDRAMP01151
SequenceGVGDLIRKAVSVIKNIV
Length17
NameUperin-3.5 (toads, amphibians, animals)
SourceUperoleia mjobergii (Australian toadlet)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus (MIC=25 µg/ml), Lactococcus lactis (MIC=3 µg/ml), Listeria innocua (MIC=25 µg/ml), Micrococcus luteus (MIC=12.5 µg/ml), Staphylococcus aureus (MIC=50 µg/ml), Staphylococcus epidermidis (MIC=12.5 µg/ml), Streptococcus uberis (MIC=12.5 µg/ml).(Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82042
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available, 15203252

Physicochemical Properties

Residues17
SequenceGVGDLIRKAVSVIKNIV
Molecular Weight1781.148
Grand Average of Hydropathy0.882
Isoelectric Point9.994
Charge at pH 7.41.553
Secondary StructureHelix: 0.471, Turn: 0.235, Sheet: 0.118
Instability Index20.276
Aromaticity0

Similar Structure Search

Candidates based on structure

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