Basic Information

IDDRAMP01188
SequenceLALKSGGWLRLFGLKDKKH
Length19
NameChensinin-1ZHa (Frogs, amphibians, animals)
SourceRana zhenhaiensis (Chinese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=35 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=9 µM).##Yeast: Candida albicans ATCC 2002 (MIC=35 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.22943378]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22943778

Physicochemical Properties

Residues19
SequenceLALKSGGWLRLFGLKDKKH
Molecular Weight2167.598
Grand Average of Hydropathy-0.321
Isoelectric Point10.462
Charge at pH 7.43.584
Secondary StructureHelix: 0.368, Turn: 0.211, Sheet: 0.316
Instability Index25.689
Aromaticity0.105

Similar Structure Search

Candidates based on structure

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