Basic Information
| ID | DRAMP01251 |
|---|
| Sequence | VWPLGLVICKALKIC |
|---|
| Length | 15 |
|---|
| Name | Dybowskin-4 (Frogs, amphibians, animals) |
|---|
| Source | Rana dybowskii (Korea brown frog) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
|---|
| Pathogen | [Ref.17698251]Gram-positive bacteria: Micrococcus luteus ATCC4698 (MIC=1.56 µg/ml), Staphylococcus aureus KCTC3881 (MIC=3.13 µg/ml), Bacillus subtilis ATCC6633 (MIC=6.25 µg/ml), Staphylococcus epidermidis ATCC12228 (MIC=6.25 µg/ml);##Gram-negative bacteria: Shigella dysenteriae ATCC9752 (MIC=30 µg/ml), Escherichia coli KCTC2433 (MIC=15 µg/ml), Klebsiella pneumoniae ATCC10031 (MIC=15 µg/ml);##Yeast: Candida albicans ATCC36232 (MIC=25 µg/ml). |
|---|
| Hemolytic Activity | [Ref:17698251] It has 47.58% hemolytic activity at 100 μg/ml against human red blood cells |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Cyclization (Cys9 and Cys15) |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 17698251 |
|---|
