Basic Information

IDDRAMP01314
SequenceFLSLLPSIVSGAVSLAKKLG
Length20
NamePhylloseptin 12 (PS-12; Frogs, amphibians, animals)
SourcePhyllomedusa azurea (Orange-legged monkey frog) (Phyllomedusa hypochondrialis azurea)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacterium: Micrococcus luteus ATCC 49732 (MIC=1.3 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17553595]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot Q17UY9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17553595

Physicochemical Properties

Residues20
SequenceFLSLLPSIVSGAVSLAKKLG
Molecular Weight2000.424
Grand Average of Hydropathy1.245
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.450, Turn: 0.350, Sheet: 0.350
Instability Index16.025
Aromaticity0.05

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.