Basic Information

IDDRAMP01351
SequenceRVCFAIPLPICH
Length12
NameTigerinin-2 (Frogs, amphibians, animals)
SourceRana tigerina (Indian bull frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Bacillus subtilis (MIC=20 µg/ml), Staphylococcus aureus ATCC 8530 (MIC=40 µg/ml), Micrococcus luteus MT 166 (MIC=20 µg/ml).##Gram-negative bacteria: Pseudomonas putida NCIM 2102 (MIC=50 µg/ml), Escherichia coli (MIC=50 µg/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=100 µg/ml).
Hemolytic Activity[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 μg/ml against rat erythrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot P82652
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11031261

Physicochemical Properties

Residues12
SequenceRVCFAIPLPICH
Molecular Weight1368.712
Grand Average of Hydropathy1.308
Isoelectric Point8.082
Charge at pH 7.40.545
Secondary StructureHelix: 0.417, Turn: 0.167, Sheet: 0.167
Instability Index49.983
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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