Basic Information

IDDRAMP01539
SequenceFKTWKRPPFQTSCWGIIKE
Length19
NameNigroain-C2 (Frogs, amphibians, animals)
SourceRana nigrovittata (Black-striped frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=27.50 µg/ml), S. aureus ATCC43300 (MIC=55.00 µg/ml), Bacillus subtilis (MIC=110.00 µg/ml);##Gram-negative bacteria: Escherichia coli ML-35P (MIC=110.00 µg/ml), Pseudomonas aeruginosa PA01 (MIC=55.00 µg/ml), Pseudomonas aeruginosa ATCC27853 (MIC=55.00 µg/ml).##Yeast: Candida albicans ATCC2002 (MIC=13.75 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.19778602]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19778602

Physicochemical Properties

Residues19
SequenceFKTWKRPPFQTSCWGIIKE
Molecular Weight2352.753
Grand Average of Hydropathy-0.721
Isoelectric Point9.787
Charge at pH 7.42.529
Secondary StructureHelix: 0.316, Turn: 0.211, Sheet: 0.053
Instability Index56.447
Aromaticity0.211

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.