Basic Information

IDDRAMP01543
SequenceDCTRWIIGINGRICRD
Length16
NameNigroain-E1 (Frogs, amphibians, animals)
SourceRana nigrovittata (Black-striped frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.19778602]Gram-positive bacterium: Staphylococcus aureus ATCC25923 (MIC=18.75 µg/ml);##Yeast: Candida albicans ATCC2002 (MIC=75 µg/ml).
Hemolytic Activity[Ref:19778602]7.62±1.6% hemolytic activity at 100 µg/ml against rabbit red cells
Cytotoxicity[Ref.19778602]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19778602

Physicochemical Properties

Residues16
SequenceDCTRWIIGINGRICRD
Molecular Weight1891.182
Grand Average of Hydropathy-0.213
Isoelectric Point8.072
Charge at pH 7.40.511
Secondary StructureHelix: 0.312, Turn: 0.188, Sheet: 0.000
Instability Index50.85
Aromaticity0.062

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