Basic Information

IDDRAMP01970
SequenceFLPFLLSALPKVFCFFSKKC
Length20
NameBrevinin-1ZHa (Frogs, amphibians, animals)
SourceRana zhenhaiensis (Chinese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=8 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=16 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=32 µM).##Yeast: Candida albicans ATCC 2002 (MIC>43 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22943778

Physicochemical Properties

Residues20
SequenceFLPFLLSALPKVFCFFSKKC
Molecular Weight2335.911
Grand Average of Hydropathy1.185
Isoelectric Point9.39
Charge at pH 7.42.501
Secondary StructureHelix: 0.500, Turn: 0.200, Sheet: 0.250
Instability Index34.145
Aromaticity0.25

Similar Structure Search

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