Basic Information

IDDRAMP01971
SequenceFLPLLLSALPSFLCLVFKKC
Length20
NameBrevinin-1ZHb (Frogs, amphibians, animals)
SourceRana zhenhaiensis (Chinese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=33 µM), Pseudomonas aeruginosa ATCC 9027 (MIC>44 µM).##Yeast: Candida albicans ATCC 2002 (MIC>44 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22943778

Physicochemical Properties

Residues20
SequenceFLPLLLSALPSFLCLVFKKC
Molecular Weight2252.864
Grand Average of Hydropathy1.67
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.550, Turn: 0.200, Sheet: 0.400
Instability Index40.505
Aromaticity0.15

Similar Structure Search

Candidates based on structure

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