Basic Information

IDDRAMP02127
SequenceGLLGGLLGPLLGGGGGGGGGLL
Length22
NameLeptoglycin (Gly-rich; Frogs, amphibians, animals)
SourceLeptodactylus pentadactylus (Smokey jungle frog) (Rana pentadactyla)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.19298834]Gram-negative bacteria: Escherichia coli ATCC 28922 (MIC=50 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=8 µM);##Fungi: Citrobacter freundii ATCC 8090 (MIC=75 µM)
Hemolytic Activity[Ref.19298834]Non-hemolytic activity was observed at 2-200 μM concentration
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P86267
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19298834

Physicochemical Properties

Residues22
SequenceGLLGGLLGPLLGGGGGGGGGLL
Molecular Weight1762.058
Grand Average of Hydropathy1.073
Isoelectric Point5.525
Charge at pH 7.4-0.443
Secondary StructureHelix: 0.364, Turn: 0.636, Sheet: 0.364
Instability Index60.027
Aromaticity0

Similar Structure Search

Candidates based on structure

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