Basic Information

IDDRAMP02130
SequenceGFLGPLLKLAAKGVAKVIPHLIPSRQQ
Length27
NameAntimicrobial peptide 1 (XT-1; Frogs, amphibians, animals)
SourceXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.11738090]Gram-positive bacteria: Staphylococcus aureus (MIC=5 µM);##Gram-negative bacteria: Escherichia coli (MIC=6 µM);##Fungi: Candida albicans (MIC=50 µM)
Hemolytic Activity[Ref.11738090]HC50=90 μM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84387
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11738090

Physicochemical Properties

Residues27
SequenceGFLGPLLKLAAKGVAKVIPHLIPSRQQ
Molecular Weight2852.465
Grand Average of Hydropathy0.422
Isoelectric Point11.264
Charge at pH 7.43.587
Secondary StructureHelix: 0.370, Turn: 0.259, Sheet: 0.296
Instability Index23.452
Aromaticity0.037

Similar Structure Search

Candidates based on structure

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