Basic Information
| ID | DRAMP02271 |
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| Sequence | GIGKFLHSAKKFGKAFVGEIMNS |
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| Length | 23 |
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| Name | Magainin-2 (Magainin II; chain of Magainins; Frogs, amphibians, animals) |
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| Source | Xenopus ruwenzoriensis (Uganda clawed frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal |
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| Pathogen | Gram-negative bacteria: Escherichia coli D31 (MIC=5 µg/ml), Klebsiella pneumoniae (MIC=10 µg/ml), Escherichia coli (MIC=50 µg/ml), Pseudomonas putida (MIC=10 µg/ml), Citrobacter freundii (MIC=30 µg/ml), Enterobacter cloacae (MIC=50 µg/ml), Pseudomonas aeruginosa (MIC=100 µg/ml), Serratia marcescens (MIC=100 µg/ml), Proteus mirabilis (MIC>100 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis (MIC=10 µg/ml), Staphylococcus aureus (MIC=50 µg/ml), Streptococcus fecalis (MIC>100 µg/ml).##Protozoa: Paramecium caudatum (MIC=10 µg/ml).##Yeast: Candida albicans (MIC=80 µg/ml). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
C0HKN6 |
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| PDB |
2MAG, 2LSA |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 3299384, 9090128, PubMed ID is not available |
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