Basic Information
| ID | DRAMP02274 |
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| Sequence | SAPRGCWTKSYPPKPCK |
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| Length | 17 |
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| Name | Ranacyclin-E (Frogs, amphibians, animals) |
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| Source | Rana esculenta (Edible frog) (Pelophylax esculentus) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.14636071]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=3 µM), Staphylococcus lentus (MIC=7 µM), Micrococcus luteus (MIC=5 µM);##Gram-negative bacteria: Yersinia pseudotuberculosis YP III (MIC=9 µM), Pseudomonas syringae pv tabaci (MIC=80 µM);##Fungi: Candida tropicalis (MIC=7.4 µM), C. guillermondii (MIC=3.4 µM), Phytophthora nicotianae spores (MIC=32 µM). |
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| Hemolytic Activity | [Ref.14636071] It has 55% hemolytic activity at 100 μM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P83663 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 14636071 |
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