Basic Information

IDDRAMP02390
SequenceRPRPNYRPRPIYRP
Length14
NameAstacidin 2 (crayfish, Arthropods, animals)
SourcePacifastacus leniusculus (signal crayfish)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Shigella flexneri ATCC 203 (MIC=0.98 µg/ml), Proteus vulgaris OX19 ATCC 6380 (MIC=7.8 µg/ml), Escherichia coli D21 (MIC=3.9 µg/ml), Psedomonas aeruginosa OT 97 (MIC=7.8 µg/ml).##Gram-positive bacteria: Bacillus megateriun B11 (MIC=1.9 µg/ml), Bacillus subtilis ATCC 6633 (MIC=1.95 µg/ml), Staphylococcus aureus JC-1 (MIC=7.8 µg/ml), Micrococcus luteus Ml 11 (MIC=10 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q0PJU7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17049601

Physicochemical Properties

Residues14
SequenceRPRPNYRPRPIYRP
Molecular Weight1838.126
Grand Average of Hydropathy-2.293
Isoelectric Point11.834
Charge at pH 7.44.552
Secondary StructureHelix: 0.214, Turn: 0.429, Sheet: 0.000
Instability Index43.143
Aromaticity0.143

Similar Structure Search

Candidates based on structure

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