Basic Information

IDDRAMP02411
SequenceGHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFHSGGGFHRGGGFHSGGSFGYR
Length53
NameArmadillidin (Glyc-rich)
SourceArmadillidium vulgare (Pillbug) (Pill woodlouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Bacillus megaterium LM101 (MIC=0.5-1.25 µM), Enterococcus faecalis LM002, Micrococcus luteus LM610, Listeria ivanovii BUG496;##Gram-negative bacteria: Escherichia coli JM83, Salmonella thyphimurium LM122, Enterobacter cloacae LM111, Citrobacter freundii LM457.##NOTE: Because of the low amount of the purified peptide, this minimal concentration activity is only tested on B. megaterium.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q64HC7
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15752546

Physicochemical Properties

Residues53
SequenceGHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFHSGGGFHRGGGFHSGGSFGYR
Molecular Weight5259.576
Grand Average of Hydropathy-0.725
Isoelectric Point12
Charge at pH 7.45.772
Secondary StructureHelix: 0.208, Turn: 0.566, Sheet: 0.019
Instability Index37.17
Aromaticity0.17

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Candidates based on structure

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