Basic Information

IDDRAMP02425
SequenceQLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY
Length32
NameIxosin-B (Ticks, Arthropods, animals)
SourceIxodes sinensis (Hard tick)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.18295522]Gram-positive bacterium: Staphylococcus aureus (MIC=2.5 µg/mL);##Gram-negative bacterium: Escherichia coli (MIC=15 µg/mL);##Yeast: Candida albicans (MIC=7.5 µg/mL).
Hemolytic Activity[Ref.18295522]Little hemolytic activity on rabbit red blood cells up to 200 μg/mL
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A7UDM9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18295522

Physicochemical Properties

Residues32
SequenceQLKVDLWGTRSGIQPEQHSSGKSDVRRWRSRY
Molecular Weight3814.191
Grand Average of Hydropathy-1.394
Isoelectric Point10.878
Charge at pH 7.43.588
Secondary StructureHelix: 0.250, Turn: 0.281, Sheet: 0.094
Instability Index86.297
Aromaticity0.094

Similar Structure Search

Candidates based on structure

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