Basic Information

IDDRAMP02446
SequenceYSKSLPLSVLNP
Length12
NameAntimicrobial protein 1 (Antimicrobial protein AN5-1)
SourcePaenibacillus alvei (Bacillus alvei)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Lactobacillus plantarum strain ATCC 8014 (MIC=32 µg/ml), Lactococcus lactis ATCC 11454 (MIC>128 µg/ml), Bacillus cereus strain ATCC 14579 (MIC=64 µg/ml), Staphylococcus aureus (MIC=64 µg/ml), Bacillus subtilis (MIC=32 µg/ml), Bacillus anthracis (MIC=128 µg/ml) and Bacillus licheniformis (MIC>128 µg/ml), Bacillus flexus (MIC=32 µg/ml);##Gram-negative bacteria: Escherichia coli strain ATCC 13076 (MIC=8 µg/ml), Salmonella enteritidis ATCC 13076 (MIC=4 µg/ml), Enterobacter spp. (MIC=16 µg/ml), Serratia marcescens (MIC=32 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot B3EWQ6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23508455

Physicochemical Properties

Residues12
SequenceYSKSLPLSVLNP
Molecular Weight1317.529
Grand Average of Hydropathy0.108
Isoelectric Point8.591
Charge at pH 7.40.552
Secondary StructureHelix: 0.417, Turn: 0.500, Sheet: 0.250
Instability Index22.817
Aromaticity0.083

Similar Structure Search

Candidates based on structure

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