Basic Information

IDDRAMP02478
SequenceIKFEPPLPPKKAHKKFWEDDGIYYPPNHNFP
Length31
NameL-amino-acid oxidase (Bm-LAO; LAAO; LAO; Snakes, reptiles, animals)
SourceBothropoides matogrossensis (Pitviper) (Bothrops neuwiedimatogrossensis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiparasitic
PathogenGram-positive bacteria: Bacillus subtilis strain ATCC 6633 (MIC=32 µM), Enterococcus faecalis strain ATCC 12953 (MIC=32 µM), Staphylococcus aureus strain ATCC 29213 (MIC=32 µM), Streptococcus pyogenes strain ATCC 19615 (MIC=8 µM);##Gram-negative bacteria: Escherichia coli strain ATCC 8739 (MIC=4 µM), Klebsiella pneumoniaee strain ATCC 13885 (MIC=2 µM), Proteus mirabilis strain ATCC 25933 (MIC=2 µM), Pseudomonas aeruginosa strain ATCC 15442 (MIC=8 µM), Salmonella typhimurium strain ATCC 14028 (MIC=8 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot B3EWI9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22438972

Physicochemical Properties

Residues31
SequenceIKFEPPLPPKKAHKKFWEDDGIYYPPNHNFP
Molecular Weight3751.25
Grand Average of Hydropathy-1.258
Isoelectric Point8.316
Charge at pH 7.40.616
Secondary StructureHelix: 0.290, Turn: 0.323, Sheet: 0.129
Instability Index63.342
Aromaticity0.194

Similar Structure Search

Candidates based on structure

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