Basic Information

IDDRAMP02522
SequenceHVINLEESFQEPEYENHLA
Length19
NameL-amino-acid oxidase (LAAO, LAO, Oh-LAAO; Snakes, reptiles, animals)
SourceOphiophagus hannah (King cobra) (Naja hannah)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Klebsiella pneumonia (MIC=0.4 µM), Pseudomonas aeruginosa (MIC=0.2 µM), Escherichia coli (MIC=0.4 µM), Escherichia coli ATCC 25922 (MIC=0.8 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=0.006 µM), S. epidermidis (MIC=0.012 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P81383, A8QL50
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9304806, 2619759, 2044840, 7886693, 21059402

Physicochemical Properties

Residues19
SequenceHVINLEESFQEPEYENHLA
Molecular Weight2298.419
Grand Average of Hydropathy-0.905
Isoelectric Point4.312
Charge at pH 7.4-5.366
Secondary StructureHelix: 0.316, Turn: 0.211, Sheet: 0.421
Instability Index62.221
Aromaticity0.105

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.