Basic Information
| ID | DRAMP02573 |
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| Sequence | QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYS |
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| Length | 62 |
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| Name | Penaeidin-3a (Pen-3a; shrimps, Arthropods, animals) |
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| Source | Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-positive bacteria: Aerococcus viridans (MIC=0.3-0.6 µM), Micrococcus luteus (MIC=1.25-2.5 µM), Bacillus megaterium (MIC=2.5-5 µM), Enterococcus fecalis (MIC>20 µM), Saphylococcus aureus (MIC>40 µM);##Gram-negative bacteria: Escherichia coli 363 (MI=10-20 µM), Vibrio vulnificus (MIC>20 µM), Salmonella thyphimurium (MIC>40 µM), Klebsiella pneumoniae (MIC>40 µM).##Fungi: Fusarium oxysporum (MIC=5-10 µM), Botrytis cinerea (MIC=5-10 µM), Neurospora crassa (MIC=1.25-2.5 µM), Aspergillus fumigatus (MIC>20 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | pyroglutamic acid |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P81058 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 9353298, 10561573, 12842879 |
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