Basic Information

IDDRAMP02741
SequenceDDTPSSRCGSGGWGPCLPIVDLLCIVHVTVGCSGGFGCCRIG
Length42
NamePelovaterin (defensin-like AMP; Gly-rich; Reptiles, animals)
SourcePelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Pseudomonas aeruginosa (EC50=0.42 µg/mL), Proteus vulgaris (EC50=0.37 µg/mL), Proteus mirabilis (EC50=8.4 µg/mL);##Gram-positive bacterium: Staphylococcus aureus (EC50=42 µg/mL).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84818
PDB 2JR3
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15877362, 18341335

Physicochemical Properties

Residues42
SequenceDDTPSSRCGSGGWGPCLPIVDLLCIVHVTVGCSGGFGCCRIG
Molecular Weight4195.823
Grand Average of Hydropathy0.545
Isoelectric Point5.296
Charge at pH 7.4-1.552
Secondary StructureHelix: 0.286, Turn: 0.381, Sheet: 0.071
Instability Index21.998
Aromaticity0.048

Similar Structure Search

Candidates based on structure

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