Basic Information

IDDRAMP02817
SequenceVDKGSYLPRPTPPRPIYNRN
Length20
NamePyrrhocoricin
SourcePyrrhocoris apterus (Sap sucking bug) (Cimex apterus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Micrococcus luteus (MIC>80 µM in L.B, P.B), Bacillus megaterium (MIC>80 µM in L.B, P.B);##Gram-negative bacteria: Escherichia coliD22 (MIC=0.3 µM in L.B, P.B), A.tumefaciens (MIC=1.25 µM in LB and 3 µM in PB), Salmonella typhimurium (MIC=5 µM in L.B and 10 µM in P.B).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P37362, P80307
PDB 4EZN resolved by X-ray.
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10076062, 8002963, 23562829

Physicochemical Properties

Residues20
SequenceVDKGSYLPRPTPPRPIYNRN
Molecular Weight2340.638
Grand Average of Hydropathy-1.395
Isoelectric Point10.267
Charge at pH 7.42.516
Secondary StructureHelix: 0.250, Turn: 0.450, Sheet: 0.050
Instability Index30.645
Aromaticity0.1

Similar Structure Search

Candidates based on structure

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