| ID | DRAMP02842 |
|---|---|
| Sequence | RRWQWR |
| Length | 6 |
| Name | LfcinB(20-25) |
| Source | bovine |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+ |
| Pathogen | [Ref.29984236] Gram-positive bacterium: Staphylococcus aureus ATCC 33591 (MIC=100 μg/ml; MBC=199 μg/ml) |
| Hemolytic Activity | [Ref.29984236] 3% hemolysis at 5 μM, 5% hemolysis at 12 μM, 5% hemolysis at 22 μM, 0% hemolysis at 50 μM, 2% hemolysis at 100 μM against human red blood cell.##[Ref.29551999] 7.1% hemolysis at 25μM, 50% hemolysis at >100μM against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P24627 |
| PDB | 1LFC |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 29984236, 29551999 |
Physicochemical Properties
| Residues | 6 |
|---|---|
| Sequence | RRWQWR |
| Molecular Weight | 987.121 |
| Grand Average of Hydropathy | -3.133 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 2.557 |
| Secondary Structure | Helix: 0.333, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 199.267 |
| Aromaticity | 0.333 |