Basic Information

IDDRAMP02896
SequenceMFTLKKSLLLLFFLGTINLSLCEQERNADEEERRDDSDKRDVEVEKRFLSTLLKVAFKVVPTLFCPITKKC
Length71
NameBrevinin-1-AJ1 antimicrobial peptide
SourceAmolops jingdongensis (Chinese torrent frog)
ActivityAntimicrobial, Antibacterial, Antifungal
PathogenNo MICs found in DRAMP database
Hemolytic Activity[Ref.22828809] 7.62% hemolytic activity at 25 μg/ml,24.58% hemolytic activity at 50 μg/ml, 83.05% hemolytic activity at 100 μg/ml, 87.65% hemolytic activity at 200 μg/ml against rabbit red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys65 and Cys71)
Linear/Cyclic/BranchedCyclic
Uniprot K7Z430
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22828809

Physicochemical Properties

Residues71
SequenceMFTLKKSLLLLFFLGTINLSLCEQERNADEEERRDDSDKRDVEVEKRFLSTLLKVAFKVVPTLFCPITKKC
Molecular Weight8310.687
Grand Average of Hydropathy-0.156
Isoelectric Point7.684
Charge at pH 7.40.201
Secondary StructureHelix: 0.352, Turn: 0.127, Sheet: 0.310
Instability Index41.107
Aromaticity0.085

Similar Structure Search

Candidates based on structure

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