Basic Information

IDDRAMP02934
SequenceRRWSFRVSYRGFSYRKSR
Length18
NamePM1-S (linear derivative of PM1)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli UB1005 (MIC=4 µg/ml), E. coli DC2 (MIC=4 µg/ml), Salmonella typhimurium (defensin-sensitive) (MIC=2 µg/ml), S. typhimurium (MIC=8 µg/ml), Pseudomonas aeruginosa K799 (MIC=32 µg/ml), P. aeruginosa Z61 (MIC=16 µg/ml);##Gram-positive bacteria: Staphylococcus aureus SAP0017 (MIC=32 µg/ml), Staphylococcus epidermidis (MIC=16 µg/ml), Enterococcus faecalis (MIC=2 µg/ml).##Yeasy: Candida albicans (MIC=64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15134657

Physicochemical Properties

Residues18
SequenceRRWSFRVSYRGFSYRKSR
Molecular Weight2394.697
Grand Average of Hydropathy-1.567
Isoelectric Point12
Charge at pH 7.46.55
Secondary StructureHelix: 0.333, Turn: 0.278, Sheet: 0.000
Instability Index60.283
Aromaticity0.278

Similar Structure Search

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