Basic Information

IDDRAMP02937
SequenceYLAFRCGRYSPCLDDGPNVNLYSCCSFYNCHKCLARLENCPKGLHYNAYLKVCDWPSKAGCTSVNKECHLWKT
Length73
NameTachycitin (crabs, Arthropods, animals)
SourceTachypleus tridentatus (Japanese horseshoe crab)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus (IC50=56 µg/ml);##Gram-negative bacteria: Escherichia coli 363 (IC50=33 µg/ml), Escherichia coli B (IC50=2 µg/ml), Salmonella typhimurium LT2 (IC50=44 µg/ml), S. minnesota R595 (IC50=41 µg/ml), Klebsiella pneumoniae (IC50=32 µg/ml).##Yeast: Candida albicans (IC50=52 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P91818
PDB 1DQC
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9010778, 10770921

Physicochemical Properties

Residues73
SequenceYLAFRCGRYSPCLDDGPNVNLYSCCSFYNCHKCLARLENCPKGLHYNAYLKVCDWPSKAGCTSVNKECHLWKT
Molecular Weight8373.591
Grand Average of Hydropathy-0.373
Isoelectric Point8.561
Charge at pH 7.43.396
Secondary StructureHelix: 0.288, Turn: 0.260, Sheet: 0.192
Instability Index66.829
Aromaticity0.137

Similar Structure Search

Candidates based on structure

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