Basic Information

IDDRAMP02993
SequenceYVPLPNVPQPGRRPFPTFPGQGPFNPKIKWPQGY
Length34
NameAbaecin (Pro-rich; insects, arthropods, invertebrates, animals)
SourceApis mellifera (Honeybee)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.2298215] Gram-negative bacteria: Agrobacterium tumefaciens Gembloux A (MIC=25-50 µg/ml), Erwinia salicis NCPPB 2530 (MIC=25-50 µg/ml), Escherichia coli NCTC 9001 (MIC=25-50 µg/ml), Escherichia coli K514 (MIC=10-25 µg/ml), Pseudomonas syringae pv.tomato NCPPB 1105 (MIC=25-50 µg/ml), Xanthomonas campestris pv. vesicatoria LMG 905 (MIC=5-10 µg/ml);##Gram-positive bacteria: Bacillus megateriurn QMB 1551 (MIC=10-25 µg/ml), Micrococcus lysodeikticus LMG 4050 (MIC=10-25 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.2298215]No cytotoxicity information found##[Ref.7961803]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot P15450?
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID2298215, 7961803

Physicochemical Properties

Residues34
SequenceYVPLPNVPQPGRRPFPTFPGQGPFNPKIKWPQGY
Molecular Weight3878.44
Grand Average of Hydropathy-0.912
Isoelectric Point10.447
Charge at pH 7.43.547
Secondary StructureHelix: 0.294, Turn: 0.471, Sheet: 0.029
Instability Index84.156
Aromaticity0.176

Similar Structure Search

Candidates based on structure

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