Basic Information

IDDRAMP03037
SequenceLNLKGIFKKVASLLT
Length15
NameEumenitin (Er-12; Insects, animals)
SourceEumenes rubronotatus (Solitary wasp)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.16762455]Gram-positive bacteria: Staphylococcus aureus ATCC 6538 (MIC>60 µM), Staphylococcus aureus ATCC 25923 (MIC=6 µM), Staphylococcus saprophytius (CS) (MIC=6 µM), Staphylococcus epidermius (CS) (MIC>60 µM), Bacillus subtilis CCT 2471 (MIC=60 µM), Bacillus thuringiensis (WT) (MIC>60 µM);##Gram-negative bacteria: Escherichia coli CCT 1371 (MIC=6 µM), Escherichia coli ATCC 25922 (MIC=6 µM), Escherichia cloacae ATCC 23355 (MIC>60 µM), Proteus mirabilis (CS) (MIC>60 µM), Pseudomonas aeruginosa ATCC 15442 (MIC=30 µM).
Hemolytic Activity[Ref.16762455]Non-hemolytic activity against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C931
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16762455, 18206199

Physicochemical Properties

Residues15
SequenceLNLKGIFKKVASLLT
Molecular Weight1645.038
Grand Average of Hydropathy0.76
Isoelectric Point10.302
Charge at pH 7.42.55
Secondary StructureHelix: 0.467, Turn: 0.200, Sheet: 0.333
Instability Index-23.327
Aromaticity0.067

Similar Structure Search

Candidates based on structure

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