Basic Information

IDDRAMP03150
SequenceMVFAYAPTCARCKSIGARYCGYGYLNRKGVSCDGQTTINSCEDCKRKFGRCSDGFITECFL
Length61
NameGambicin (Insects, animals)
SourceAnopheles albimanus (mosquito)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiparasitic
PathogenGram-negative bacterium: E. coli (MIC=6.25-12.5 µM);##Gram-positive bacterium: M. luteus (MIC=25-50 µM).##Fungus: N. crassa.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11606751

Physicochemical Properties

Residues61
SequenceMVFAYAPTCARCKSIGARYCGYGYLNRKGVSCDGQTTINSCEDCKRKFGRCSDGFITECFL
Molecular Weight6766.745
Grand Average of Hydropathy-0.195
Isoelectric Point8.693
Charge at pH 7.43.072
Secondary StructureHelix: 0.246, Turn: 0.230, Sheet: 0.148
Instability Index41.389
Aromaticity0.131

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