Basic Information
| ID | DRAMP03180 |
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| Sequence | AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRGRRHS |
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| Length | 75 |
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| Name | ASABF-alpha (ASABF; nematodes, animals) |
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| Source | Ascaris suum (Pig roundworm) (Ascaris lumbricoides) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.10991847]Gram-negative bacteria: Escherichia coli JM109 (IC50=50 µg/ml), Proteus vulgaris ATCC 13315 (IC50=10 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC6538P (IC50=0.6 µg/ml), Bacillus subtilis ATCC6633 (IC50=1.2 µg/ml), Micrococcus luteus ATCC398 (IC50=0.8 µg/ml). |
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| Hemolytic Activity | [Ref.10991847]4.5% hemolytic activity at 1000 μg/ml against human red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P90683 |
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| PDB |
2D56 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8940016, 10991847 |
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