Basic Information
| ID | DRAMP03236 |
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| Sequence | GFFGNTWKKIKGKADKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYLLKYYGKKALQKASEKL |
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| Length | 69 |
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| Name | M-zodatoxin-Lt8a (M-ZDTX-Lt8a; Cytoinsectotoxin-1a, CIT-1a; spiders, Arthropods, animals) |
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| Source | Lachesana tarabaevi (Spider) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Insecticidal |
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| Pathogen | [Ref.18215128]Gram-positive bacteria: Arthrobacter globiformis VKM Ac-1112 (MIC=0.5 µM), Bacillus subtilis VKM B-501 (MIC=0.9 µM), Micrococcus luteus (MIC>30 µM), Staphylococcus aureus (MIC>30 µM);##Gram-negative bacteria: Escherichia coli C600 (MIC=0.5 µM), E. coli DH5alpha (MIC=0.9 µM), E. coli MH1 (MIC=0.5 µM), Pseudomonas aeruginosa PAO1 (MIC=1.9 µM), Pseudomonas fluorescens VKM B-894 (MIC=3.8 µM). |
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| Hemolytic Activity | [Ref.18215128]EC50=6 μM against human erythrocytes |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P85253, B3W6H9 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 18215128 |
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