Basic Information
| ID | DRAMP03357 |
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| Sequence | LQDAALGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK |
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| Length | 38 |
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| Name | Cryptdin related sequence peptide (CRS4C-1a; Rodents, mammals, animals) |
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| Source | Mus musculus (Mouse) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-positive bacteria: Enterococcus faecalis (LC=1.9 µM), Lactobacillus fermentum DSM 20052 (LC=1.1 µM), Strepococcus pyogenes clinical isolate (LC=0.4 µM), Listeria monocytogenes type 1 clinical isolate (LC=1.4 µM);##Gram-negative bacteria: Escherichia coli strain D21 (LC=2.4 µM), Salmonella typhimurium ATCC 14028 (LC=1.7 µM).##NOTE: Dimerized peptide was two- to fourfold more potent than monomeric peptide. LC, Lethal concentrations. |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
Q70LV2, Q70LV8, Q70LV7, Q70LV6, Q70LV4 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15235601 |
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