Basic Information

IDDRAMP03472
SequenceMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR
Length74
NamecgUbiquitin
SourceCrassostrea gigas (Pacific oyster)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22858580]Gram-positive bacteria: B. subtilis KCTC1021 (MIC=0.4 µM), S. aureus RM4220 (MIC=4.7 µM), S. iniae FP5229 (MIC=0.9 µM);##Gram-negative bacteria: E. coli D31 (MIC=0.2 µM), E. coli ML35p (MIC=1.4 µM), P. aeruginosa KCTC2004 (MIC=0.6 µM), S. flexneri KCTC2517 (MIC=0.7 µM), S. sonnei KCTC2009 (MIC=1.2 µM), A. hydrophila KCTC2358 (MIC=0.7 µM), V. parahemolyticus KCCM41664 (MIC=1.1 µM);##Yeast: C. albicans KCTC7965 (MIC=9.4 µM).
Hemolytic Activity[Ref.22858580]Non-hemolytic against human red blood cells up to 100 μg/mL
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22858580

Physicochemical Properties

Residues74
SequenceMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR
Molecular Weight8450.633
Grand Average of Hydropathy-0.492
Isoelectric Point6.562
Charge at pH 7.4-0.69
Secondary StructureHelix: 0.311, Turn: 0.162, Sheet: 0.243
Instability Index36.239
Aromaticity0.041

Similar Structure Search

Candidates based on structure

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