Basic Information

IDDRAMP03521
SequenceDIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS
Length37
NameProline-rich antimicrobial peptide 1 (Insects, animals)
SourceGalleria mellonella (Greater wax moth)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
PathogenGram-positive bacterium: Micrococcus luteus(MIC=55.0 µM).##Fungi: Pichia pastoris (MIC=16.5 µM), Zygosaccharomyces marxianus (MIC=16.5 µM), Schizosaccharomyces pombe (MIC=11 µM), candida wickerhamii (MIC=16.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P85214
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11995991, 17194500

Physicochemical Properties

Residues37
SequenceDIQIPGIKKPTHRDIIIPNWNPNVRTQPWQRFGGNKS
Molecular Weight4322.887
Grand Average of Hydropathy-1.057
Isoelectric Point11
Charge at pH 7.43.587
Secondary StructureHelix: 0.270, Turn: 0.351, Sheet: 0.000
Instability Index11.13
Aromaticity0.081

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