| ID | DRAMP03580 |
|---|---|
| Sequence | DSHAKRHHGYKRKFHEKHHSHRGY |
| Length | 24 |
| Name | His3-(20-43)-peptide (Histatin 5; derivatives: Dh-5; Clinical) |
| Source | Homo sapiens (Human) |
| Activity | Antimicrobial, Antibacterial, Antifungal |
| Pathogen | Yeast: Candida albicans (100% inhibition at 54 nmol), Cryptococcus neoformans. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P15516, Q16243, Q502Z1 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 3286634 |
Physicochemical Properties
| Residues | 24 |
|---|---|
| Sequence | DSHAKRHHGYKRKFHEKHHSHRGY |
| Molecular Weight | 3036.293 |
| Grand Average of Hydropathy | -2.454 |
| Isoelectric Point | 10.283 |
| Charge at pH 7.4 | 4.8 |
| Secondary Structure | Helix: 0.125, Turn: 0.167, Sheet: 0.083 |
| Instability Index | 37.867 |
| Aromaticity | 0.125 |