Basic Information

IDDRAMP03679
SequenceRFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFP
Length43
NameCathelicidin-2 (Bactenecin-5, Bac5; ChBac5; ruminant, animals)
SourceCapra hircus (Goat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli (MIC=1 µg/ml), Salmonella typhimurium (MIC=1 µg/ml), Pseudomonas aeruginosa (MIC=1 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC<2 µg/ml), Listeria monocytogenes (MIC<2 µg/ml) and Bacillus subtilis (MIC<2 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P82018, Q4JFB9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10417180

Physicochemical Properties

Residues43
SequenceRFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFP
Molecular Weight5162.151
Grand Average of Hydropathy-1.014
Isoelectric Point12
Charge at pH 7.49.557
Secondary StructureHelix: 0.256, Turn: 0.512, Sheet: 0.000
Instability Index134.395
Aromaticity0.163

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