Basic Information

IDDRAMP03701
SequenceQLEARFEPKQRNFRKRELDFEKLFANMPDY
Length30
NameImcroporin (Arthropods, animals)
SourceIsometrus maculatus (Lesser brown scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.19451300]Gram-positive bacteria: Micrococcus luteus(MIC=20μg/ml), Bacillus thuringiensis(MIC=50μg/ml), Staphylococcus aureus(MIC=20μg/ml), Bacillus subtilis(MIC=50μg/ml).
Hemolytic Activity[Ref.19451300]5% hemolytic activity at 40 μg/mL, 20% hemolytic at 50 μg/mL, 70% hemolytic aactivity at 100 μg/mL against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot C7B247
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19451300

Physicochemical Properties

Residues30
SequenceQLEARFEPKQRNFRKRELDFEKLFANMPDY
Molecular Weight3817.293
Grand Average of Hydropathy-1.37
Isoelectric Point8.429
Charge at pH 7.40.553
Secondary StructureHelix: 0.267, Turn: 0.133, Sheet: 0.333
Instability Index40.727
Aromaticity0.167

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