Basic Information

IDDRAMP03766
SequenceGWINEEKIQKKIDEKIGNNILGGMAKAVVHKLAKGEFQCVANIDTMGNCETHCQKTSGEKGFCHGTKCKCGKPLSY
Length76
NameHeteroscorpine-1 (HS-1; defensins; Arthropods, animals)
SourceHeterometrus laoticus (Thai giant scorpion)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Bacillus subtilis (5.2 mm);##Gram-negative bacteria: Klebsiella pneumoniae (10.57 mm), Pseudomonas aeruginosa (6.4 mm).##NOTE: Diameter of clear zone from disc diffusion assay. Total protein is 6.25 µmole.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C2F4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17056081

Physicochemical Properties

Residues76
SequenceGWINEEKIQKKIDEKIGNNILGGMAKAVVHKLAKGEFQCVANIDTMGNCETHCQKTSGEKGFCHGTKCKCGKPLSY
Molecular Weight8298.562
Grand Average of Hydropathy-0.553
Isoelectric Point8.792
Charge at pH 7.43.495
Secondary StructureHelix: 0.211, Turn: 0.237, Sheet: 0.197
Instability Index19.687
Aromaticity0.053

Similar Structure Search

File for ID DRAMP03766 does not exist.

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