| ID | DRAMP03877 |
|---|---|
| Sequence | KKWWWKWKKW |
| Length | 10 |
| Name | LFB-KW (derivative of bovine lactoferrin with residues substitution) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=11.25 µM), Escherichia coli (wild strain) (MIC=7.50 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=11.25 µM), Enterococcus faecalis ATCC 29212 (MIC=22.5 µM). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 13677384 |
Physicochemical Properties
| Residues | 10 |
|---|---|
| Sequence | KKWWWKWKKW |
| Molecular Weight | 1589.926 |
| Grand Average of Hydropathy | -2.4 |
| Isoelectric Point | 10.602 |
| Charge at pH 7.4 | 4.545 |
| Secondary Structure | Helix: 0.500, Turn: 0.000, Sheet: 0.000 |
| Instability Index | 9 |
| Aromaticity | 0.5 |